STRUCTURAL GENOMIX AND COMPAQ TO BUILD MULTI-MILLION DOLLAR STATE-OF-THE-ART
DATA CENTER FOR 
STRUCTURAL INFORMATICS

Compaq's High Performance Technical Computing Will Advance 
SGX's Drug Discovery Efforts

SAN DIEGO, Calif. - September 20, 2001 - Structural GenomiX (SGX) today
announced a multi-million dollar agreement with Compaq Computer Corporation
(NYSE:CPQ) to develop SGX's high performance structural informatics systems.
SGX will purchase a complete Compaq technology solution including Compaq
AlphaServer* systems running Tru64* UNIX*, market leading Compaq ProLiant*
industry-standard servers running Linux, StorageWorks* and services.
Compaq's Alpha chip technology and leadership in building high performance
computing systems will advance SGX's drug discovery efforts by increasing
SGX's ability to run its high-throughput protein modeling, molecular
dynamics, and chemical docking programs on a genomic scale.

As the leader in high performance computing for genomics and proteomics,
Compaq was selected based on its ability to expand SGX's drug discovery
efforts through its industry leading technology and experience in life
sciences computing.  The technology and services provided by Compaq will
assist SGX and its partners in target identification and validation, lead
selection and screening, and optimization of compounds for binding and
selectivity, with the goal of improving drug efficacy as well as predicting
and avoiding toxicity and negative side effects. As part of the agreement,
Compaq will build and install a high performance computing system consisting
initially of 200 Tru64 UNIX-based AlphaServer DS10L systems, two AlphaServer
GS80 systems in a TruCluster, one AlphaServer ES40 system, and a
140-processor Linux-based Compaq ProLiant server cluster.  SGX will also
receive system upgrades, support services, and early access to new
technologies, including access to the Intel* Itanium* microprocessor
architecture.

"Compaq's technology and support will enhance our structural informatics
capabilities, allowing us to model and compare more target structures and
computationally explore more lead compounds than competing systems," said
Tim Harris, Ph.D., SGX's President and CEO. "In the search for an IT
partner, SGX selected an organization that has dedicated its efforts and
resources to the life sciences field. I believe our relationship with Compaq
in structural genomics computing is the foundation for a comprehensive
understanding of protein structures and small molecule interactions and will
rapidly scale up SGX's drug discovery process."

"Compaq is pleased to be selected as Structural GenomiX's information
technology provider to power their leading-edge structure based drug
discovery efforts," said Bill Blake, Vice President of Compaq's High
Performance Technical Computing Group.  "SGX is an emerging player in the
genome technology arena, and Compaq's IT solutions will assist SGX in
significantly expanding their research capabilities and achieving their
long-term business goals."

Structural GenomiX (SGX) is a leader in experimental and computational
structural biology, transforming genomic information into structural
templates for drug discovery. SGX technologies include advanced
bioinformatics tools for target selection and structure annotation,
automation of molecular biology and protein biochemistry, high-throughput
crystallization, protein structure prediction by comparative modeling and ab
initio methods, synthetic and computational chemistry, and rapid co-complex
structure determination. SGX has a dedicated world-class facility for the
collection of macromolecular X-ray diffraction data at the Advanced Photon
Source (APS) at the U.S. Department of Energy's Argonne National Laboratory.
SGX's programs include
3D-IDTM, a program leveraging SGX technologies toward the discovery and
design of novel anti-infectives, protein kinase and nuclear receptor
structural genomics programs, and a five-year $13M strategic alliance with
the Cystic Fibrosis Foundation focused on membrane protein structure
prediction and crystallography.  SGX is headquartered in San Diego with
additional locations in San Francisco and Argonne, IL. 

For more information, please visit the Company website at www.stromix.com
<http://www.stromix.com>.

Compaq, the Compaq logo, AlphaServer, ProLiant and StorageWorks are
trademarks of Compaq Information Technologies Group, L.P.  Intel and Itanium
are trademarks of Intel Corporation.  UNIX is a trademark of The Open Group.
All other trademarks contained herein are the property of their respective
owners.