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Today, IBM Life Sciences announced that it has forged one of its most important alliances -- with a leading software company that will allow chemists and biologists to develop new drugs faster, more efficiently, and at lower costs. Accelrys -- perhaps the most important software vendor in the rapidly-growing life sciences market segment -- will make IBM its technology partner, with IBM eServer systems and DiscoveryLink the platforms of choice for its complete spectrum of drug discovery and drug development applications. Accelrys will lead with the IBM servers -- including "Regatta" UNIX servers and IBM Linux clusters -- as well as DiscoveryLink data integration software. This announcement is especially significant because it will result in powerful IT solutions that will touch literally every part of a pharmaceutical company's research and development organization, offering new efficiencies and shrinking the drug discovery process. Stacy Simpson Media Relations IBM Corporation Route 100, Somers, NY 10589 Ph: 914-766-4123 (t/l: 826-4123) E: stacysim@us.ibm.com 01/07/2002 IBM and Accelrys Form Global Strategic Alliance to Transform Drug Research and Development Broad-reaching Commitment To Direct IT Resources Toward Helping Drug Makers Shorten Development Cycles ARMONK, N.Y., and SAN DIEGO, January 7, 2002 . . . IBM (NYSE: IBM) and Accelrys, Inc., a wholly owned subsidiary of Pharmacopeia, Inc. (NASDAQ: PCOP), today announced a global strategic alliance to enhance drug research and development (R&D) operations by creating a collaborative information technology environment for chemists and biologists to develop new drugs faster, more efficiently, and at lower costs. Through the agreement, Accelrys, one of the world's leading software developers in life sciences, will become a premier partner in IBM's PartnerWorld for Developers Program, a status reserved for top-tier strategic alliance partners. IBM and Accelrys will team up, with each company contributing key technologies, to help pharmaceutical and biotechnology companies and medical research centers improve their R&D operations and shorten the development cycle for new drugs. "This alliance represents one of the most significant and influential relationships for IBM in life sciences," said Dr. Caroline Kovac, general manager, IBM Life Sciences. "IBM and Accelrys share the common goal of developing innovative technology solutions that will benefit the life sciences community and accelerate drug discovery and development. Our relationship will leverage IBM's cutting-edge supercomputing technologies and Accelrys' broad software expertise to drive the new levels of efficiency in pharmaceutical R&D." Alliance Highlights Under the terms of the four-year alliance, IBM becomes Accelrys' preferred information technology and services partner for life sciences. IBM's eServer* systems will be Accelrys' server family of choice for life sciences applications. Through its collaboration with IBM, Accelrys will accelerate the delivery of its Discovery Studio** platform, which promises to be the industry's first technology platform to fully support the entire drug discovery process. Discovery Studio is a set of Accelrys technologies that will offer broad access to key life sciences applications, while enabling effective capture and reuse of critical scientific information and knowledge, whether generated by Accelrys' portfolio of software products, in-house or by third parties. "The drug industry is asking for a consolidated, integrated platform for sharing data and knowledge," said Dr. Michael Stapleton, chief operating officer and executive vice president of Accelrys. "We chose IBM as our technology partner because of their commitment to the market we serve and their strength in high-performance computing, software, and services that align with our goals. Through IBM's and Accelrys' complementary technologies, we can help customers increase the productivity of their drug development efforts and get more successful drug candidates through the development cycle faster." Other key elements of the alliance include: -- Accelrys will enable its software applications to run optimally on IBM eServer systems for UNIX, Windows NT*** and Linux***. Accelrys applications, which support R&D processes ranging from early isolation of target genes and proteins associated with particular diseases, through synthesizing chemical compounds that will work on these targets, to pre-clinical testing and drug delivery, are used by virtually every major pharmaceutical and most major biotechnology and chemical companies. -- Accelrys becomes a premier member of IBM's PartnerWorld for Developers Program (www.developer.ibm.com), which offers business partners a wide range of sales, education, training, and technical support programs. This worldwide program is designed to help software developers reach broader markets faster and lower their costs of doing business. -- Accelrys will use IBM eServer p690 (code named "Regatta") systems running AIX*, IBM eServer xSeries* systems running Linux and Windows NT, and the IBM eServer Cluster 1300 Linux system for software development, testing and knowledge management applications. -- Accelrys will combine IBM DiscoveryLink* data integration technology with the new Discovery Studio platform. -- IBM and Accelrys will jointly market Discovery Studio offerings for IBM platforms and middleware. -- IBM and Accelrys will provide a range of joint consulting and implementation services for deploying solutions that combine mutual technologies. "This announcement is the latest example of how the emerging bioscience sector is a major catalyst for growth in high-performance technical computing, in the same way that the application of simulation and modeling was to defense, manufacturing and petroleum in years past," said Debra Goldfarb, group vice president, International Data Corporation. "The IBM-Accelrys alliance should be welcome news in an industry feeling tremendous pressure to innovate, and could result in impressive market share gains for both companies." According to the TOP500 Supercomputer list (www.top500.org), IBM systems account for 160 of the world's 500 most powerful high-performance computers and half of the top 10 more powerful machines -- more than any other vendor. The list was published in November 2001 by supercomputing experts Jack Dongarra from the University of Tennessee and Erich Strohmaier and Hans Meuer of the University of Mannheim (Germany). "Life science IT solutions will have dramatic growth in the next several years," said Dorman Followwill, Vice President, HealthCare, Frost & Sullivan. "This reflects the historic convergence of IT and biology, where the limits of biology now equal the limits of computing. It is difficult to overstate the future role of IT in modernizing the drug discovery and development process through high-performance computing, services and software for translating reams of genomic/proteomic data into clinically useful information. IBM and Accelrys are well positioned to lead the way in this space." About IBM IBM Life Sciences brings together IBM resources, from research, services and e-business expertise to data and storage management and high-performance computing, to offer new solutions for the life sciences market, including biotechnology, genomic, e-health, pharmaceutical, and agri-science industries. The fastest way to get more information about IBM Life Sciences is through its Web site, http://www.ibm.com/solutions/lifesciences. About Accelrys Accelrys is a leading provider of software for computation, simulation and the management and mining of scientific data used by biologists, chemists, and materials scientists for product design, drug discovery, and development. Accelrys' platform technology and consulting services enable enterprise-wide solutions tailored to today's leading research organizations. The company's three main centers of excellence are in San Diego, CA, Princeton, NJ, and Cambridge, UK. These centers combine research and product development with facilities to support significant collaborative projects. Technology centers in Madison, WI, and Leeds, UK house expert product development teams focused on informatics products. Accelrys is a subsidiary of Pharmacopeia, Inc. (Nasdaq: PCOP). Accelrys was launched in June 2001, combining leading software companies Molecular Simulations Inc., Synopsys Scientific Systems, Oxford Molecular, GCG, and Synomics Ltd. More information on Accelrys can be found at http://www.accelrys.com. # # # * Indicates trademark or registered trademark of IBM Corporation. ** Indicates trademark or registered trademark of Accelrys, Inc. *** Indicates trademark or registered trademark. Safe Harbor Statement When used anywhere in this document, the words "expects," "believes," "anticipates," "estimates" and similar expressions are intended to identify forward-looking statements. Forward-looking statements herein may include statements addressing future financial and operating results of Pharmacopeia and the timing, benefits and other aspects of the proposed merger. Pharmacopeia has based these forward-looking statements on its current expectations about future events. Such statements are subject to risks and uncertainties including, but not limited to, the successful implementation of Pharmacopeia's strategic plans, the acceptance of new products, the obsolescence of existing products, the resolution of existing and potential future patent issues, additional competition, changes in economic conditions, and other risks described in documents Pharmacopeia has filed with the SEC, including its most recent report on Form 10-K and subsequent reports on Form 10-Q. All forward-looking statements in this document are qualified entirely by the cautionary statements included in this document and such filings. These risks and uncertainties could cause actual results to differ materially from results expressed or implied by forward-looking statements contained in this document. These forward-looking statements speak only as of the date of this document. Pharmacopeia disclaims any undertaking to publicly update or revise any forward-looking statements contained herein to reflect any change in its expectations with regard thereto or any change in events, conditions or circumstances on which any such statement is based.